A comparison
Bryan Johnson’s Blueprint Protocol specifies what enters the body. MAVI specifies the room the body lives in. The two halves of a complete longevity practice, side by side.
The most popular longevity protocol of the last decade is, almost by definition, an input protocol. Blueprint specifies the food, the supplements, the sleep schedule, the exercise dose, the diagnostic cadence. It is rigorous, public, and measured. It is also, on its own, half of the picture.
The other half is the room. The home is a twenty-three-hour-a-day exposure surface that no input protocol can reach. MAVI is the design discipline that specifies it.
| Blueprint | MAVI | |
|---|---|---|
| Subject of optimisation | The body. Food, supplements, sleep schedule, exercise dose, diagnostic cadence. | The architecture around the body. Air, water, light, sound, temperature, materials, microbiology, EMF, mind, habits. |
| Methodology | Public input protocol with measured biomarker outputs. Iterates against personal data. | Peer-reviewed framework with measured environmental outputs. Iterates against the latest science. |
| Unit of measurement | Organ-system biomarkers (HRV, glucose, sleep stages, lipid panel, etc.). | The MAVI Score, a 0 to 100 composite across 129 environmental factors in ten domains. |
| Core asset | Time, discipline, and the practitioner's own body. | The residence and its specification. |
| Cost profile | Recurring (food, supplements, diagnostics, equipment). | One-time at design specification, then near-zero. Material specification is the cheapest moment to specify and the most expensive to retrofit. |
| Reversibility | Immediate. Stop the protocol, biology returns to baseline within weeks. | Slow but durable. Architecture is the variable that compounds. |
| Evidence base | Self-quantified plus selected peer-reviewed sources. | Peer-reviewed across environmental health, circadian biology, building science, materials chemistry, environmental psychology. |
| Public price | Open-source protocol; supplements via Blueprint Stack. | Snapshot free. Diagnostic CHF 999. Living Diagnostic CHF 999 + CHF 199/month. Higher tiers by invitation. |
| Practitioner profile | Bryan Johnson, public-facing. Backed by his own clinical team. | Kas Bordier, Geneva. Two decades at the intersection of UHNW residential, hospitality, and longevity medicine. |
| Time to first signal | Days to weeks (sleep, energy, glucose). | Seven minutes (Snapshot). Twenty-four hours (Diagnostic). |
| What it cannot do | Cannot redesign the room the body lives in twenty-three hours a day. | Cannot replace what enters the body, the supplements taken, the food eaten, the schedule kept. |
| Stack position | Body half of the longevity stack. | Architecture half of the longevity stack. |
The single sentence: Blueprint optimises the biology. MAVI optimises the architecture the biology lives inside. Either alone is partial; together they describe the full longevity stack.
If you are practising Blueprint and have not yet specified the room, the Snapshot of your address is free. Seven minutes, no card required.