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References

The peer-reviewed papers and authoritative sources behind the MAVI 129™ framework. Curated, not exhaustive. A full per-residence reference list is generated for each Diagnostic client; this page is the public foundation.

Air

  1. World Health Organization (2021). WHO global air quality guidelines: particulate matter (PM2.5 and PM10), ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide. WHO Press, Geneva. link

    The current authoritative thresholds. PM2.5 annual guideline: 5 µg/m³.

  2. Allen JG, MacNaughton P, Satish U, Santanam S, Vallarino J, Spengler JD (2016). Associations of cognitive function scores with carbon dioxide, ventilation, and volatile organic compound exposures in office workers. Environmental Health Perspectives 124(6), 805-812. doi:10.1289/ehp.1510037

    Foundational evidence that CO₂ above ~1000 ppm degrades decision-making.

  3. IARC Working Group (2012). Chemical agents and related occupations: a review of human carcinogens (Volume 100F), Formaldehyde. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. link

    Formaldehyde classified as Group 1 human carcinogen.

Water

  1. European Parliament (2020). Directive (EU) 2020/2184 on the quality of water intended for human consumption. Official Journal of the European Union. link

    PFAS limit 100 ng/L for the regulated sum of twenty.

  2. Wallace LA (1997). Human exposure and body burden for chloroform and other trihalomethanes. Critical Reviews in Environmental Science and Technology 27(2), 113-194. doi:10.1080/10643389709388514

    Foundational paper on dermal and inhalation absorption from shower water.

Light

  1. Brown TM, Brainard GC, Cajochen C, et al. (2022). Recommendations for daytime, evening, and nighttime indoor light exposure to best support physiology, sleep, and wakefulness in healthy adults. PLOS Biology 20(3), e3001571. doi:10.1371/journal.pbio.3001571

    The consensus paper that defines target melanopic EDL by time of day.

  2. CIE (2018). CIE S 026/E:2018, CIE System for Metrology of Optical Radiation for ipRGC-Influenced Responses to Light. Commission Internationale de l'Éclairage. link

    The standard that operationalises melanopic EDL as a measurement framework.

  3. Phillips AJK, Vidafar P, Burns AC, et al. (2019). High sensitivity and interindividual variability in the response of the human circadian system to evening light. PNAS 116(24), 12019-12024. doi:10.1073/pnas.1901824116

    Evening melatonin suppression occurs at far lower light levels than previously assumed.

Sound

  1. World Health Organization Regional Office for Europe (2018). Environmental noise guidelines for the European Region. WHO. link

    Chronic 45 dB(A) night noise raises cardiovascular risk independently of subjective sleep quality.

Temperature

  1. Okamoto-Mizuno K, Mizuno K (2012). Effects of thermal environment on sleep and circadian rhythm. Journal of Physiological Anthropology 31(1), 14. doi:10.1186/1880-6805-31-14

    Defines the narrow thermoneutral envelope for sleep.

Materials

  1. European Chemicals Agency (ECHA) (2023). Annex XV restriction report, Per- and polyfluoroalkyl substances (PFAS). ECHA. link

    The EU-wide proposal to restrict PFAS in textiles, cookware, and consumer products.

  2. Dodson RE, Nishioka M, Standley LJ, Perovich LJ, Brody JG, Rudel RA (2012). Endocrine disruptors and asthma-associated chemicals in consumer products. Environmental Health Perspectives 120(7), 935-943. doi:10.1289/ehp.1104052

    Phthalate plasticisers and other endocrine disruptors in everyday building and home products.

Microbiology

  1. World Health Organization Regional Office for Europe (2009). WHO guidelines for indoor air quality: dampness and mould. WHO. link

    The authoritative residential-mould risk and remediation guidance.

  2. Kirjavainen PV, Karvonen AM, Adams RI, et al. (2019). Farm-like indoor microbiota in non-farm homes protects children from asthma development. Nature Medicine 25(7), 1089-1095. doi:10.1038/s41591-019-0469-4

    Evidence that indoor microbiome diversity correlates with immune resilience.

Technology

  1. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans (2013). Non-ionizing radiation, Part 2: Radiofrequency electromagnetic fields. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Volume 102. link

    Radiofrequency EMF classified as Group 2B possible human carcinogen.

Mind

  1. Ulrich RS (1984). View through a window may influence recovery from surgery. Science 224(4647), 420-421. doi:10.1126/science.6143402

    The foundational paper on the biophilic effect of a single tree at the window.

  2. Browning WD, Ryan CO, Clancy JO (2014). 14 Patterns of Biophilic Design, Improving Health & Well-Being in the Built Environment. Terrapin Bright Green. link

    The canonical pattern language for biophilic design at residential resolution.

Habits

  1. Levine JA (2002). Non-exercise activity thermogenesis (NEAT). Best Practice & Research Clinical Endocrinology & Metabolism 16(4), 679-702. doi:10.1053/beem.2002.0227

    The foundational paper on incidental movement and metabolic outcome.

Field

  1. Attia P, Gifford B (2023). Outlive: The Science and Art of Longevity. Harmony Books.

    The Medicine 3.0 framework, body-side prevention as the central act of medicine.

  2. Sinclair DA, LaPlante MD (2019). Lifespan: Why We Age, and Why We Don't Have To. Atria Books.

    The popular synthesis of the sirtuin / NAD / senolytics research programme.

  3. Huberman AD, et al. (Ongoing). Huberman Lab, circadian biology, light, temperature, and behaviour. Stanford School of Medicine and the Huberman Lab podcast. link

    Public translation of circadian-biology research into actionable protocols.

  4. Johnson B, et al. (Ongoing). Blueprint Protocol, open-source body-input protocol with measured biomarker outputs. Bryan Johnson and the Blueprint team. link

    The most-documented body-side longevity protocol in the public field. MAVI specifies the architecture half; Blueprint specifies the body half.

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