The home is a microbial ecosystem, and the architectural decisions made at design (humidity envelope, ventilation, material specification) determine whether that ecosystem trains the immune system or stresses it.
What microbiology actually is, in a residence
Three populations matter:
- Pathogenic and inflammatory: mould species, mycotoxins, dust mites, cockroach and rodent dander, biofilms in plumbing. The populations that produce illness when their environment favours them.
- Commensal: the bacteria, archaea, fungi, and viruses that populate every indoor surface. The training set the adult immune system needs.
- Hygiene-critical surfaces: kitchen counters, bathroom fixtures, bedding, soft furnishings. Where active hygiene matters because the population on the surface contacts food, mucosa, or skin daily.
The MAVI 129™ Microbiology domain scores all three.
The thresholds that matter
- Relative humidity: target 40 to 50%. Below 30%, mucosal surfaces dry. Above 60% sustained, mould and mites flourish.
- Surface temperature: should not drop more than 3 °C below ambient anywhere in the envelope; condensation produces the moisture that mould needs.
- Air exchange rate: 0.35 air changes per hour minimum (ASHRAE residential), higher in kitchens and bathrooms.
- Bedding wash temperature: 60 °C weekly for dust-mite control.
- Indoor microbiome diversity: the marker that correlates with immune resilience (Kirjavainen et al. 2019).
Where the design decisions actually live
For most residential projects, the microbiology outcome is set by four decisions:
Humidity control. The envelope, the ventilation, the cooking and bathing exhaust, the moisture-bearing materials. A 40 to 50% RH envelope across seasons is the single biggest preventive measure.
Thermal-bridge elimination. Where surface temperature falls below dew point, condensation forms and mould follows. Thermography at design-stage and again at commissioning catches the problem geography before the mould does.
Ventilation rate and topology. Bathrooms and kitchens need extract; sleeping zones need fresh air; the whole house needs balanced exchange. HRV/ERV systems are the design-grade answer; window-only ventilation is the workaround.
Material biology. Natural-fibre soft furnishings shed less microplastic but retain more dust-mite reservoir without the right wash cycle. Hard floors with rugs that can be washed are the cleanest topology in bedrooms. Antimicrobial-treated finishes are usually counterproductive, they kill the commensal population alongside the problem.
What “microbiology” looks like in a MAVI Diagnostic
A residence’s Microbiology score is built from humidity logging by room, thermography of the envelope (cold spots predict condensation), surface dust analysis where the framework requires (mould-spore species, mite-allergen concentration, microbiome diversity profile), and an HVAC and ventilation review (extract rates, balance, filter chain).
The output is a 0 to 100 sub-score and a priority intervention list. For most residences, the highest-leverage interventions are humidity envelope control and thermal-bridge remediation.
The single thing to do today
Look in the corners of every room for mould spotting (especially bathrooms, behind furniture against external walls, around windows). Run a humidity logger for two weeks. Most problems are visible if you know where to look. The MAVI Snapshot flags geographies where mould risk is high; the Diagnostic does the per-room thermography and microbiology work.